A. W. F. Edwards (2003) argued that analyses that consider only locus-by-locus variation can be misleading because they ignore correlation structure among multiple genetic loci, and that correlated allele-frequency patterns across loci can contain information enabling stable population classification.
January 01, 2003
high
temporal
Conceptual critique emphasizing multivariate structure ('correlations among loci') as a source of classificatory information.
A 1963 analysis by L. L. Cavalli-Sforza and A. W. F. Edwards derived an evolutionary tree for 15 human populations using genetic data without prior assumptions about tree form, illustrating that multivariate correlations can recover population structure.
January 01, 1963
high
temporal
Historical example demonstrating that tree-like population structure can be inferred from correlations in gene-frequency data.