Scientists Create Human Eggs from Skin Cells
Researchers at Oregon Health & Science University led by Shoukhrat Mitalipov report in Nature Communications (Sept. 30, 2025) that they produced human eggs whose nuclear DNA came from adult skin cells by replacing donor-egg DNA and inducing a novel cell-division pathway dubbed 'mitomeiosis.' The team generated 82 functional eggs, fertilized some with sperm, and found about 9% of resulting embryos reached the blastocyst stage, though all embryos exhibited genetic abnormalities that currently preclude implantation.
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🔍 Key Facts
- Lead researcher: Shoukhrat Mitalipov at Oregon Health & Science University; study published Sept. 30, 2025 in Nature Communications
- Output: 82 functional eggs created; 9% of fertilized embryos developed to blastocyst stage
- Caveat: all embryos showed genetic abnormalities preventing safe implantation; technique used somatic-cell nuclear transfer and a process the authors call 'mitomeiosis'
📍 Contextual Background
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