Study links diet drinks to higher liver disease risk
At United European Gastroenterology Week in Berlin this week, researchers analyzing UK Biobank data on ~120,000 adults over about a decade reported that both sugar‑sweetened and artificially sweetened beverages were associated with increased risk of metabolic dysfunction‑associated steatotic liver disease (MASLD), with diet drinks tied to an even higher risk (~60%) than sugary drinks (~50%). Lead author Lihe Liu said substituting water for either beverage type was associated with up to a 15% lower risk; the study is not yet peer‑reviewed but adds to concern that artificial sweeteners may adversely affect metabolism and gut bacteria.
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📌 Key Facts
- Cohort: ~120,000 adults without baseline liver disease, followed ~10 years (UK Biobank)
- Risk: ~50% higher MASLD risk for sugary drinks; ~60% higher for diet/zero‑sugar drinks
- Substitution: Replacing either beverage with water linked to up to 15% lower risk
- Mortality: Artificially sweetened drinks were also linked to higher liver‑related mortality
- Status: Findings presented at UEG Week; full study not yet peer‑reviewed