October 09, 2025
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Study links diet drinks to higher liver disease risk

At United European Gastroenterology Week in Berlin this week, researchers analyzing UK Biobank data on ~120,000 adults over about a decade reported that both sugar‑sweetened and artificially sweetened beverages were associated with increased risk of metabolic dysfunction‑associated steatotic liver disease (MASLD), with diet drinks tied to an even higher risk (~60%) than sugary drinks (~50%). Lead author Lihe Liu said substituting water for either beverage type was associated with up to a 15% lower risk; the study is not yet peer‑reviewed but adds to concern that artificial sweeteners may adversely affect metabolism and gut bacteria.

Health Science

📌 Key Facts

  • Cohort: ~120,000 adults without baseline liver disease, followed ~10 years (UK Biobank)
  • Risk: ~50% higher MASLD risk for sugary drinks; ~60% higher for diet/zero‑sugar drinks
  • Substitution: Replacing either beverage with water linked to up to 15% lower risk
  • Mortality: Artificially sweetened drinks were also linked to higher liver‑related mortality
  • Status: Findings presented at UEG Week; full study not yet peer‑reviewed

đź“° Sources (1)