Entity: liver
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liver

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Gut bacteria in the small intestine can metabolize dietary fructose before that fructose reaches the liver.
medium physiological
Microbial metabolism of sugars in the small intestine can reduce the amount of sugar delivered to the liver.
Dietary fibers that feed gut microbes (prebiotics) can decrease the amount of dietary fructose reaching the liver and thereby have the potential to reduce hepatic fat accumulation and oxidative stress associated with early fatty liver disease.
medium clinical potential
Prebiotic fibers support microbial consumption of fructose in the gut, which may lower liver exposure to fructose and its downstream metabolic effects.