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Entity: PGC-1 alpha
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PGC-1 alpha

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Exercise increases levels of the protein PGC-1 alpha in muscle, and PGC-1 alpha activates genes that promote mitochondrial biogenesis.
high descriptive
PGC-1 alpha is a regulator that links exercise to increased mitochondrial production in muscle.
physiology molecular biology
Well-exercised male mice appear to pass fitness to
The protein NCoR1 inhibits PGC-1 alpha, acting as a regulatory brake on PGC-1 alpha–driven activation of mitochondrial and metabolic genes.
high descriptive
NCoR1 functions as a negative regulator of PGC-1 alpha–mediated metabolic and mitochondrial programs.
molecular biology gene regulation
Well-exercised male mice appear to pass fitness to

Related Topics

gene regulation molecular biology physiology