A 2024 study led by QIMR Berghofer Medical Research Institute and published in Nature Communications identified roughly 7,000 DNA changes linked to depression across both sexes and approximately 6,000 additional genetic variations unique to women, totaling about 13,000 DNA changes associated with depression.
January 01, 2024
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Genetic association findings from a large-scale analysis of depression cases.
A 2024 genetic analysis reported that genetic factors appear to contribute more to depression risk in women than in men, with nearly twice as many depression-linked genetic signals identified in women compared with men.
January 01, 2024
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Comparison of the number of depression-associated genetic signals by sex.
A 2024 study found that depression-related genetic variants identified in women show stronger overlap with genetic signals linked to metabolic traits compared with those identified in men, suggesting a genetic connection between depression in women and metabolic symptoms such as weight change or altered energy.
January 01, 2024
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Reported genetic overlap between depression-associated variants and metabolic trait loci in female cases.